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中文名称： CYP11B1抗原（重组蛋白）
英文名称： CYP11B1 Antigen (Recombinant Protein)
别 名： FHI; CPN1; CYP11B; P450C11
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from C terminal 250 amino acids of human CYP11B1 |
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Full name: |
cytochrome P450, family 11, subfamily B, polypeptide 1 |
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Synonyms: |
FHI; CPN1; CYP11B; P450C11 |
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Swissprot: |
P15538 |
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Gene Accession: |
BC096285 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. |
