Full name: |
phosphodiesterase 4D, cAMP-specific |
Synonyms: |
DPDE3; PDE43; STRK1; ACRDYS2; HSPDE4D; PDE4DN2 |
Swissprot: |
Q08499 |
Gene Accession: |
BC008390 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins. |