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  • PAK5抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16992
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: PAK5抗原(重组蛋白)

英文名称: PAK5 Antigen (Recombinant Protein)

别       名 PAK7

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 420-719 amino acids of human PAK5

技术规格

Full name:

p21 (RAC1) activated kinase 5

Synonyms:

PAK7

Swissprot:

Q9P286

Gene Accession:

BC024179

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]