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  • OCLN抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16973
    • 应用 : 仅供科研使用
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    • 货期 : 现货
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中文名称: OCLN抗原(重组蛋白)

英文名称: OCLN Antigen (Recombinant Protein)

别      名: BLCPMG

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 266-522 amino acids of human OCLN

技术规格

Full name:

Occludin

Synonyms:

BLCPMG

Swissprot:

Q16625

Gene Accession:

BC029886

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.