Full name: |
2'-5'-oligoadenylate synthetase-like |
Synonyms: |
OASLd, TRIP14, TRIP-14, p59OASL, p59 OASL, p59-OASL |
Swissprot: |
Q15646 |
Gene Accession: |
BC117408 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes, the 2-5A synthetases or OASs |