中文名称: 兔抗MANF多克隆抗体
英文名称: Anti-MANF rabbit polyclonal antibody
别 名: ARP; ARMET
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: MANF
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Applications:
ELISA, IHC
Name of antibody:
MANF
Immunogen:
Synthetic peptide of human MANF
Full name:
mesencephalic astrocyte-derived neurotrophic factor
Synonyms:
ARP; ARMET
SwissProt:
P55145
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human thyroid cancer and Human colon cancer
IHC Recommend dilution:
100-300