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中文名称： CENPC抗原（重组蛋白）
英文名称： CENPC Antigen (Recombinant Protein)
别 名： MIF2; hcp-4; CENP-C; CENPC1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human CENPC |
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Full name: |
centromere protein C |
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Synonyms: |
MIF2; hcp-4; CENP-C; CENPC1 |
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Swissprot: |
Q03188 |
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Gene Accession: |
BC030695 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. |
