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    MYH7抗原（重组蛋白）

    MYH7抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW16895
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存：40
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中文名称： MYH7抗原（重组蛋白）

英文名称： MYH7 Antigen (Recombinant Protein)

别      名： CMH1, MPD1, SPMD, SPMM, CMD1S, MYHCB

储      存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to a C terminal 300 amino acids of human MYH7

技术规格

Full name:

myosin, heavy chain 7, cardiac muscle, beta

Synonyms:

CMH1, MPD1, SPMD, SPMM, CMD1S, MYHCB

Swissprot:

P12883

Gene Accession:

BC112171

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.