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  • MUC20抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16884
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中文名称: MUC20抗原(重组蛋白)

英文名称: MUC20 Antigen (Recombinant Protein)

别      名: MUC-20

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MUC20

技术规格

Full name:

mucin 20, cell surface associated

Synonyms:

MUC-20

Swissprot:

Q8N307

Gene Accession:

BC029267

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.