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  • MCM8抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16831
    • 应用 : 仅供科研使用
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中文名称: MCM8抗原(重组蛋白)

英文名称: MCM8 Antigen (Recombinant Protein)

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MCM8

技术规格

Full name:

minichromosome maintenance complex component 8

Synonyms:

REC, C20orf154, dJ967N21.5

Swissprot:

Q9UJA3

Gene Accession:

BC080656

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.