欢迎来到上海通蔚!

021-54845833/15800441009

品质保证 · 通蔚试剂

当前位置: 首页 > 科研产品 > 科研抗体 > 其他抗体 > MCM2抗原(重组蛋白)

产品中心

  • MCM2抗原(重组蛋白)

    规格:
    数量:

    购买数量

    价格:
    • 品牌 : 通蔚生物
    • 目录号 : TW16822
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存:40
  • 商品详情
  • 参考文献
  • 说明书下载
  • 商品评论0
  • 相关产品

中文名称: MCM2抗原(重组蛋白)

英文名称: MCM2 Antigen (Recombinant Protein)

别       名: BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MCM2

技术规格

Full name:

minichromosome maintenance complex component 2

Synonyms:

BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN

Swissprot:

P49736

Gene Accession:

BC007670

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.