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中文名称： BABAM2抗原（重组蛋白）
英文名称： BABAM2 Antigen (Recombinant Protein)
别 名： BRE; BRCC4; BRCC45
储 存： 冷冻（-20℃）
相关类别： 抗原 、
概 述：
|
Fusion protein corresponding to a region derived from 30-147 amino acids of human BABAM2 |
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Full name: |
BRISC and BRCA1 A complex member 2 |
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Synonyms: |
BRE; BRCC4; BRCC45 |
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Swissprot: |
Q9NXR7 |
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Gene Accession: |
BC001251 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016] |
