欢迎来到上海通蔚!

021-54845833/15800441009

品质保证 · 通蔚试剂

当前位置: 首页 > 科研产品 > 科研抗体 > 其他抗体 > LEF1抗原(重组蛋白)

产品中心

  • LEF1抗原(重组蛋白)

    规格:
    数量:

    购买数量

    价格:
    • 品牌 : 通蔚生物
    • 目录号 : TW16765
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存:40
  • 商品详情
  • 参考文献
  • 说明书下载
  • 商品评论0
  • 相关产品

中文名称: LEF1抗原(重组蛋白)

英文名称: LEF1 Antigen (Recombinant Protein)

别      名: LEF-1; TCF10; TCF7L3; TCF1ALPHA

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from C terminal 300 amino acids of human LEF1

技术规格

Full name:

lymphoid enhancer-binding factor 1

Synonyms:

LEF-1; TCF10; TCF7L3; TCF1ALPHA

Swissprot:

Q9UJU2

Gene Accession:

BC050632

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.