ELISA试剂盒

PCR试剂盒

生化试剂盒

细胞系

细胞库

基础培养基

完全培养基

原代细胞

细胞专用培养基

菌株

科研抗体

生化试剂

病理染色液

食品检测类试剂盒

LC12A1抗原（重组蛋白）

规格：

数量：

购买数量

价格：￥

品牌 : 通蔚生物
目录号 : TW16760
应用 : 仅供科研使用
保存条件 : 低温保存
货期 : 现货
商品库存：40

中文名称： LC12A1抗原（重组蛋白）

英文名称： LC12A1 Antigen (Recombinant Protein)

别名： BSC1; NKCC2

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 80-172 amino acids of human SLC12A1

技术规格

Full name:	Solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Synonyms:	BSC1; NKCC2
Swissprot:	Q13621
Gene Accession:	BC040138
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

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