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中文名称：ASB2抗原（重组蛋白）
英文名称： ASB2 Antigen (Recombinant Protein)
别 名： ASB-2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 340-535 amino acids of human ASB2 |
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Full name: |
ankyrin repeat and SOCS box containing 2 |
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Synonyms: |
ASB-2 |
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Swissprot: |
Q96Q27 |
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Gene Accession: |
BC032354 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
