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  • KLK7抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16750
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: KLK7抗原(重组蛋白)

英文名称: KLK7 Antigen (Recombinant Protein)

别       名: hK7, SCCE, PRSS6

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 30-253 amino acids of human KLK7

技术规格

Full name:

kallikrein-related peptidase 7

Synonyms:

hK7, SCCE, PRSS6

Swissprot:

P49862

Gene Accession:

BC032005

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.