欢迎来到上海通蔚！
请登录 ▏ 注册 ▏ 购物车 ▏ 帮助

021-54845833/15800441009

品质保证 · 通蔚试剂

当前位置: 首页 > 科研产品 > 科研抗体 > 其他抗体 > KCNA5抗原（重组蛋白）

产品中心

最新产品

  • 其他抗体
    KCNA5抗原（重组蛋白）

    KCNA5抗原（重组蛋白）

    规格：
    数量：

    购买数量

    价格：￥
    • 品牌 : 通蔚生物
    • 目录号 : TW16740
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存：40
  • 商品详情
  • 参考文献
  • 说明书下载
  • 商品评论0
  • 相关产品
中文名称： KCNA5抗原（重组蛋白）

英文名称： KCNA5 Antigen (Recombinant Protein)

别       名： HK2, HCK1, PCN1, ATFB7, HPCN1, KV1.5

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to a region derived from 517-613 amino acids of human KCNA5

技术规格

Full name:

potassium voltage-gated channel, shaker-related subfamily, member 5

Synonyms:

HK2, HCK1, PCN1, ATFB7, HPCN1, KV1.5

Swissprot:

P22460

Gene Accession:

BC099665

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).