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  • GSTA3抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16684
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: GSTA3抗原(重组蛋白)

英文名称: GSTA3 Antigen (Recombinant Protein)

别     名: GTA3; GSTA3-3

储     存: 冷冻(-20℃)

相关类别: 抗原

概     述

Full length fusion protein

技术规格

Full name:

glutathione S-transferase alpha 3

Synonyms:

GTA3; GSTA3-3

Swissprot:

Q16772

Gene Accession:

BC020619

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.