Background: |
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
DCP1A |
Immunogen: |
Fusion protein of human DCP1A |
Full name: |
decapping mRNA 1A |
Synonyms: |
SMIF; SMAD4IP1; HSA275986; Nbla00360 |
SwissProt: |
Q9NPI6 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human cervical cancer and human colon cancer |
IHC Recommend dilution: |
100-300 |