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Background: |
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DCLK1 |
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Immunogen: |
Synthetic peptide of human DCLK1 |
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Full name: |
doublecortin-like kinase 1 |
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Synonyms: |
CL1; DCLK; CLICK1; DCDC3A; DCAMKL1 |
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SwissProt: |
O15075 |
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IHC positive control: |
Human gastric cancer and human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
