中文名称:兔抗DBF4多克隆抗体
Background: |
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
Applications: |
WB |
Name of antibody: |
DBF4 |
Immunogen: |
Synthesized peptide derived from N-terminal of human DBF4. |
Full name: |
DBF4 zinc finger |
Synonyms: |
ASK; CHIF; DBF4A; ZDBF1 |
SwissProt: |
Q9UBU7 |
WB Predicted band size: |
77 kDa |
WB Positive control: |
NIH/3T3 cells lysate treated with H2O2 (100uM, 30mins) and COS-7 cells lysate treated with PMA (125mg/ml, 30mins) |
WB Recommended dilution: |
500-3000 |