相关类别: 抗原
概 述
Full name: |
echinoderm microtubule associated protein like 4 |
Synonyms: |
C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120 |
Swissprot: |
Q9HC35 |
Gene Accession: |
BC008685 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. |