兔抗CYP27A1多克隆抗体

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

Applications:

ELISA, IHC

Name of antibody:

CYP27A1

Immunogen:

Fusion protein of human CYP27A1

Full name:

cytochrome P450, family 27, subfamily A, polypeptide 1

Synonyms:

CTX; CP27; CYP27

SwissProt:

Q02318

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

50-200