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Background: |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CYP11B2 |
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Immunogen: |
Synthetic peptide of human CYP11B2 |
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Full name: |
cytochrome P450 family 11 subfamily B member 2 |
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Synonyms: |
CPN2; ALDOS; CYP11B; CYP11BL; CYPXIB2; P450C18; P-450C18; P450aldo |
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SwissProt: |
P19099 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
50-300 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
HEPG2 cell lysate |
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WB Recommended dilution: |
500-200 |
