兔抗CYP11B2多克隆抗体

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Applications:

ELISA, WB, IHC

Name of antibody:

CYP11B2

Immunogen:

Synthetic peptide of human CYP11B2

Full name:

cytochrome P450 family 11 subfamily B member 2

Synonyms:

CPN2; ALDOS; CYP11B; CYP11BL; CYPXIB2; P450C18; P-450C18; P450aldo

SwissProt:

P19099

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

50-300

WB Predicted band size:

58 kDa

WB Positive control:

HEPG2 cell lysate

WB Recommended dilution:

500-200