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  • DDX52 抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16519
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: DDX52 抗原(重组蛋白)

英文名称: DDX52 Antigen (Recombinant Protein)

别     名: DExD-box helicase 52; ROK1; HUSSY19

储     存: 冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 400-599 amino acids of human DDX52

技术规格

Full name:

DExD-box helicase 52

Synonyms:

ROK1; HUSSY19

Swissprot:

Q9Y2R4

Gene Accession:

BC041785

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DEAD box protein 52 (DDX52), also known as ATP-dependent RNA helicase ROK1-like or HUSSY-19, is a 599 amino acid protein belonging to the DEAD box helicase family. Localized to the nucleus, DDX52 is phosphorylated by ATM or ATR upon DNA damage. DDX52 contains one helicase ATP-binding domain and one helicase C-terminal domain.