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  • DCK抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16492
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: DCK抗原(重组蛋白)

英文名称: DCK Antigen (Recombinant Protein)

储     存: 冷冻(-20℃)

相关类别: 抗原

概     述

Full length fusion protein

技术规格

Full name:

deoxycytidine kinase

Swissprot:

P27707

Gene Accession:

BC114617

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.