ELISA试剂盒

PCR试剂盒

生化试剂盒

细胞系

细胞库

基础培养基

完全培养基

原代细胞

细胞专用培养基

菌株

科研抗体

生化试剂

病理染色液

食品检测类试剂盒

DCPS 抗原（重组蛋白）

规格：

数量：

购买数量

价格：￥

品牌 : 通蔚生物
目录号 : TW16488
应用 : 仅供科研使用
保存条件 : 低温保存
货期 : 现货
商品库存：60

中文名称： DCPS 抗原（重组蛋白）

英文名称： DCPS Antigen (Recombinant Protein)

别名： decapping enzyme, scavenger; ARS; DCS1; HSL1; HINT5; HINT-5; HSPC015

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 2-337 amino acids of human DCPS

技术规格

Full name:	decapping enzyme, scavenger
Synonyms:	ARS; DCS1; HSL1; HINT5; HINT-5; HSPC015
Swissprot:	Q96C86
Gene Accession:	BC014532
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP (PubMed:22985415). May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP (PubMed:14523240). Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death.

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