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    DAND5抗原（重组蛋白）

    DAND5抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW16475
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称： DAND5抗原（重组蛋白）

英文名称： DAND5 Antigen (Recombinant Protein)

别     名： SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3

储     存： 冷冻（-20℃）

相关类别： 抗原

概     述

Full length fusion protein

技术规格

Full name:

DAN domain family member 5, BMP antagonist

Synonyms:

SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3

Swissprot:

Q8N907

Gene Accession:

BC113476

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.