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Background: |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CYP2D6 |
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Immunogen: |
Synthetic peptide of human CYP2D6 |
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Full name: |
cytochrome P450, family 2, subfamily D, polypeptide 6 |
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Synonyms: |
CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1 |
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SwissProt: |
P10635 |
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IHC positive control: |
Human gastric cancer and human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
K562 cells |
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WB Recommended dilution: |
200-1000 |
