欢迎来到上海通蔚！
请登录 ▏ 注册 ▏ 购物车 ▏ 帮助

021-54845833/15800441009

品质保证 · 通蔚试剂

当前位置: 首页 > 科研产品 > 科研抗体 > 其他抗体 > DAZ1 抗原（重组蛋白）

产品中心

最新产品

  • 其他抗体
    DAZ1 抗原（重组蛋白）

    DAZ1 抗原（重组蛋白）

    规格：
    数量：

    购买数量

    价格：￥
    • 品牌 : 通蔚生物
    • 目录号 : TW16469
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存：60
  • 商品详情
  • 参考文献
  • 说明书下载
  • 商品评论0
  • 相关产品
中文名称： DAZ1 抗原（重组蛋白）

英文名称： DAZ1 Antigen (Recombinant Protein)

别     名： deleted in azoospermia 1; DAZ; SPGY

储     存： 冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 414-613 amino acids of human DAZ1

技术规格

Full name:

deleted in azoospermia 1

Synonyms:

DAZ; SPGY

Swissprot:

Q9NQZ3

Gene Accession:

BC114927

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains.