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  • CYB5R1 抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16453
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存:60
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中文名称: CYB5R1 抗原(重组蛋白)

英文名称: CYB5R1 Antigen (Recombinant Protein)

别     名: cytochrome b5 reductase 1; B5R1; B5R2; B5R.1; NQO3A2; humb5R2

储     存: 冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 29-305 amino acids of human CYB5R1

技术规格

Full name:

cytochrome b5 reductase 1

Synonyms:

B5R1; B5R2; B5R.1; NQO3A2; humb5R2

Swissprot:

Q9UHQ9

Gene Accession:

BC018732

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

NADH-cytochrome b5 reductases participate in a variety of physiological processes including biosynthesis of cholesterol, methemoglobin reduction of erythrocytes, elongation of fatty acids and metabolism of drugs. CYB5R1 (cytochrome b5 reductase 1), also known as NADH-cytochrome b5 reductase 1, B5R1, NQO3A2, humb5R2 or NAD(P)H:quinone oxidoreductase type 3 polypeptide A2, is a 305 amino acid single-pass membrane protein that contains one FAD-binding FR-type domain and belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. Widely expressed, CYB5R1 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.