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021-54845833/15800441009
中文名称： 兔抗TRPC4AP多克隆抗体
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Background: |
TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TRPC4AP |
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Immunogen: |
Fusion protein of human TRPC4AP |
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Full name: |
transient receptor potential cation channel, subfamily C, member 4 associated protein |
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Synonyms： |
TRUSS; TRRP4AP; PPP1R158; C20orf188 |
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SwissProt: |
Q8TEL6 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
30-150 |
