Background: |
Bonzo (also designated STRL33.3) and BOB (brother of Bonzo; also designated GRP15) are seven-transmembrane, G protein-coupled receptors that are closely related to chemokine receptor family members. In conjunction with CD4, several chemokine receptors are known to serve as receptors for HIV-1 entry into cells. Bonzo and BOB are utilized by simian immunodeficiency virus (SIV), HIV-2 and M-tropic HIV-1 for cell entry. Bonzo and BOB are both expressed in lymphoid tissues, and BOB is also expressed in colon. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
CXCR6 |
Immunogen: |
Fusion protein of human CXCR6 |
Full name: |
chemokine (C-X-C motif) receptor 6 |
Synonyms: |
BONZO; CD186; STRL33; TYMSTR |
SwissProt: |
O00574 |
IHC positive control: |
Human gastric cancer and human thyroid cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
39 kDa |
WB Positive control: |
Human fetal brain and mouse brain tissue |
WB Recommended dilution: |
500-2000 |