中文名称: CPSF1 抗原(重组蛋白)
相关类别: 抗原
概 述
Full name: |
cleavage and polyadenylation specific factor 1 |
Synonyms: |
CPSF160; P/cl.18; HSU37012 |
Swissprot: |
Q10570 |
Gene Accession: |
BC017232 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]). |