中文名称:兔抗CTNND2多克隆抗体
Background: |
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: |
ELISA, WB |
Name of antibody: |
CTNND2 |
Immunogen: |
Synthetic peptide of human CTNND2 |
Full name: |
catenin delta 2 |
Synonyms: |
GT24; NPRAP |
SwissProt: |
Q9UQB3 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
133 kDa |
WB Positive control: |
Mouse brain tissue and Human cerebrum tissue lysates |
WB Recommended dilution: |
200-1000 |