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    • 品牌 : 通蔚生物
    • 目录号 : TW16229
    • 应用 : 仅限于科研使用
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中文名称: ATRIP抗原(重组蛋白)


英文名称: ATRIP Antigen (Recombinant Protein)

别       名: ATR interacting protein

相关类别: 抗原

储       存: 冷冻(-20℃)

概述

Fusion protein corresponding to a region derived from 592-791 amino acids of human ATRIP

技术规格

Full name:

ATR interacting protein

Swissprot:

Q8WXE1

Gene Accession:

BC030597

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.