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中文名称： CENPM抗原（重组蛋白）
相关类别： 抗原
概 述
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Full name: |
centromere protein M |
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Synonyms: |
PANE1; CENP-M; C22orf18; bK250D10.2 |
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Swissprot: |
Q9NSP4 |
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Gene Accession: |
BC000705 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]). |
