Background: |
This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Applications: |
WB, IHC |
Name of antibody: |
CTDSP1 |
Immunogen: |
Synthesized peptide derived from N-terminal of human CTDSP1. |
Full name: |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
Synonyms: |
NIF3; SCP1; NLIIF; NLI-IF |
SwissProt: |
Q9GZU7 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
29 kDa |
WB Positive control: |
Huvec cells and Hela cells lysates |
WB Recommended dilution: |
500-3000 |