中文名称:ANKHD1抗原(重组蛋白)
英文名称: ANKHD1 Antigen (Recombinant Protein)
别 名: MASK; VBARP; PP2500
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ANKHD1 |
Full name: |
ankyrin repeat and KH domain containing 1 |
Synonyms: |
MASK; VBARP; PP2500 |
Swissprot: |
Q8IWZ3 |
Gene Accession: |
BC009420 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. |