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中文名称：ANAPC5 抗原（重组蛋白）
英文名称： ANAPC5 Antigen (Recombinant Protein)
别 名： anaphase promoting complex subunit 5; APC5
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 300 amino acids of human ANAPC5 |
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Full name: |
anaphase promoting complex subunit 5 |
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Synonyms: |
APC5 |
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Swissprot: |
Q9UJX4 |
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Gene Accession: |
BC006301 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. |
