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英文名称： AMBRA1 Antigen (Recombinant Protein)
别 名： autophagy/beclin-1 regulator 1; DCAF3; WDR94
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
Fusion protein corresponding to a region derived from 691-880 amino acids of human AMBRA1
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Full name: |
autophagy/beclin-1 regulator 1 |
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Synonyms: |
DCAF3; WDR94 |
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Swissprot: |
Q9C0C7 |
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Gene Accession: |
BC045609 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3. |
