中文名称:AGBL3 抗原(重组蛋白)
英文名称: AGBL3 Antigen (Recombinant Protein)
别 名: ATP/GTP binding protein-like 3
相关类别: 抗原
储 存: 冷冻(-20℃)
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human AGBL3 |
Full name: |
ATP/GTP binding protein-like 3 |
Swissprot: |
Q8NEM8 |
Gene Accession: |
BC030651 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
CCP3 (cytosolic carboxypeptidase 3), also known as AGBL3 (ATP/GTP-binding protein-like 3), is a 1,001 amino acid cytosolic protein that exists as four alternatively spliced isoforms and belongs to the peptidase M14 family. As a metallocarboxypeptidase, CCP3 binds one zinc ion per subunit and may play a role in the processing of tubulin. The gene that encodes CCP3 consists of approximately 161,457 bases and maps to human chromosome 7q33. Housing over 1,000 genes, chromosome 7 comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |