兔抗GJB2多克隆抗体

Background:

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

Applications:

ELISA, IHC

Name of antibody:

GJB2

Immunogen:

Synthetic peptide of human GJB2

Full name:

gap junction protein, beta 2, 26kDa

Synonyms：

HID, KID, PPK, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A

SwissProt:

P29033

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

100-300