兔抗CORO2A多克隆抗体

Background:

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.

Applications:

ELISA, IHC

Name of antibody:

CORO2A

Immunogen:

Fusion protein of human CORO2A

Full name:

coronin 2A

Synonyms:

IR10; WDR2; CLIPINB

SwissProt:

Q92828

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and Human liver cancer

IHC Recommend dilution:

20-100