Background: |
The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. |
Applications: |
WB, IHC |
Name of antibody: |
CLOCK |
Immunogen: |
Synthesized peptide derived from Internal of human Clock. |
Full name: |
clock circadian regulator |
Synonyms: |
KAT13D; bHLHe8 |
SwissProt: |
O15516 |
IHC positive control: |
Human skeletal muscle tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
95 kDa |
WB Positive control: |
Huvec cells lysate |
WB Recommended dilution: |
500-3000 |