Background: |
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
CLN5 |
Immunogen: |
Synthetic peptide of human CLN5 |
Full name: |
ceroid-lipofuscinosis, neuronal 5 |
Synonyms: |
NCL |
SwissProt: |
O75503 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
40-200 |
WB Predicted band size: |
41 kDa |
WB Positive control: |
231 cell lysate |
WB Recommended dilution: |
200-1000 |