Background: |
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. |
Applications: |
WB |
Name of antibody: |
GGA2 |
Immunogen: |
Fusion protein of human GGA2 |
Full name: |
golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
Synonyms: |
GGA2; FLJ20966; KIAA1080; VEAR |
SwissProt: |
Q9UJY4 |
WB Predicted band size: |
67 kDa |
WB Positive control: |
Brain tissue |
WB Recommended dilution: |
500-2000 |