中文名称:兔抗CISH多克隆抗体
Background: |
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
CISH |
Immunogen: |
Fusion protein of human CISH |
Full name: |
cytokine inducible SH2 containing protein |
Synonyms: |
CIS; G18; SOCS; CIS-1; BACTS2 |
SwissProt: |
Q9NSE2 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer and Human thyroid cancer |
IHC Recommend dilution: |
100-300 |