Background: |
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). |
Applications: |
ELISA, WB |
Name of antibody: |
CIAO2A |
Immunogen: |
Fusion protein of human CIAO2A |
Full name: |
cytosolic iron-sulfur assembly component 2A |
Synonyms: |
CIA2A; FAM96A |
SwissProt: |
Q9H5X1 |
WB Predicted band size: |
18 kDa |
WB Positive control: |
Human fetal intestines tissue |
WB Recommended dilution: |
200-1000 |