Background: |
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. |
Applications: |
WB, IHC, IF |
Name of antibody: |
CHPF |
Immunogen: |
Synthesized peptide derived from internal of human CHSS2. |
Full name: |
chondroitin polymerizing factor |
Synonyms: |
CSS2; CHSY2 |
SwissProt: |
Q8IZ52 |
IHC positive control: |
Human cervix carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
85 kDa |
WB Positive control: |
LOVO cells and K562 cells lysates |
WB Recommended dilution: |
500-3000 |
IF positive control: |
MCF-7 cells |
IF Recommend dilution: |
100-500 |